KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
VPS39
All Species:
34.24
Human Site:
T226
Identified Species:
62.78
UniProt:
Q96JC1
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96JC1
NP_056104.2
886
101809
T226
A
V
G
Q
D
D
L
T
V
V
L
N
E
E
G
Chimpanzee
Pan troglodytes
XP_510331
886
101752
T226
A
V
G
Q
D
D
L
T
V
V
L
N
E
E
G
Rhesus Macaque
Macaca mulatta
XP_001102792
886
101693
T226
A
V
G
Q
D
D
L
T
V
V
L
N
E
E
G
Dog
Lupus familis
XP_849407
886
101720
T226
A
V
G
Q
D
D
L
T
V
V
L
N
E
E
G
Cat
Felis silvestris
Mouse
Mus musculus
Q8R5L3
886
101674
T226
A
V
G
Q
D
D
L
T
V
V
L
N
E
E
G
Rat
Rattus norvegicus
XP_001075756
886
101629
T226
A
V
G
Q
D
D
L
T
V
V
L
N
E
E
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518189
1309
145152
C649
V
L
N
E
E
G
T
C
T
Q
K
C
A
L
N
Chicken
Gallus gallus
NP_001026365
875
100503
T215
A
V
G
Q
D
D
L
T
V
V
L
N
E
E
G
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
A4IG72
863
97029
L229
L
L
A
A
P
G
G
L
G
M
F
A
N
A
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_650702
876
100146
G214
L
I
R
N
N
M
L
G
I
S
K
D
S
Y
L
Honey Bee
Apis mellifera
XP_392710
866
100055
S220
V
L
G
K
D
S
Q
S
F
V
M
D
T
R
G
Nematode Worm
Caenorhab. elegans
NP_001041163
923
104932
D238
N
E
I
V
V
T
T
D
I
W
G
Q
R
P
A
Sea Urchin
Strong. purpuratus
XP_798217
824
94304
S220
A
L
G
R
D
N
M
S
I
I
I
D
S
E
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
99.3
98
N.A.
97.4
96.8
N.A.
59.2
92.7
N.A.
26.4
N.A.
35.4
42.4
31.7
51.5
Protein Similarity:
100
99.8
99.7
99.3
N.A.
98.9
98.5
N.A.
62.8
96.1
N.A.
46.8
N.A.
55.6
62
52.5
68.4
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
0
100
N.A.
0
N.A.
6.6
26.6
0
33.3
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
20
100
N.A.
13.3
N.A.
33.3
60
6.6
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
62
0
8
8
0
0
0
0
0
0
0
8
8
8
8
% A
% Cys:
0
0
0
0
0
0
0
8
0
0
0
8
0
0
0
% C
% Asp:
0
0
0
0
70
54
0
8
0
0
0
24
0
0
0
% D
% Glu:
0
8
0
8
8
0
0
0
0
0
0
0
54
62
8
% E
% Phe:
0
0
0
0
0
0
0
0
8
0
8
0
0
0
0
% F
% Gly:
0
0
70
0
0
16
8
8
8
0
8
0
0
0
70
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
8
8
0
0
0
0
0
24
8
8
0
0
0
0
% I
% Lys:
0
0
0
8
0
0
0
0
0
0
16
0
0
0
0
% K
% Leu:
16
31
0
0
0
0
62
8
0
0
54
0
0
8
8
% L
% Met:
0
0
0
0
0
8
8
0
0
8
8
0
0
0
0
% M
% Asn:
8
0
8
8
8
8
0
0
0
0
0
54
8
0
8
% N
% Pro:
0
0
0
0
8
0
0
0
0
0
0
0
0
8
0
% P
% Gln:
0
0
0
54
0
0
8
0
0
8
0
8
0
0
0
% Q
% Arg:
0
0
8
8
0
0
0
0
0
0
0
0
8
8
0
% R
% Ser:
0
0
0
0
0
8
0
16
0
8
0
0
16
0
0
% S
% Thr:
0
0
0
0
0
8
16
54
8
0
0
0
8
0
0
% T
% Val:
16
54
0
8
8
0
0
0
54
62
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _